What Is Peri-implantitis?
Peri-implantitis is a pathological condition that begins as inflammation in the soft tissues around a dental implant and progresses to the supporting bone, causing progressive bone loss. According to the current definition accepted at the 2017 World Workshop, it is a plaque-related disease characterized by progressive loss of the bone supporting the implant. Just as periodontitis is inflammation that has reached the bone around a natural tooth, peri-implantitis serves the same function around an implant. The difference is in how the implant attaches to bone compared to a natural tooth: implants lack a periodontal ligament, and bone fuses directly to the implant surface (osseointegration). This difference determines the progression pattern of peri-implantitis and the challenges in treating it.Anatomy Around the Implant
To understand peri-implantitis, it's important to know the implant and its surrounding structures:- Implant body (fixture): The titanium (rarely zirconia) screw placed in the bone. It replaces the tooth root
- Abutment: The intermediate component screwed onto the implant body that holds the crown
- Crown: The tooth-shaped top portion attached to the abutment
- Peri-implant mucosa: The gum-like soft tissue around the implant. It differs in structure from natural tooth gums; it has no periodontal ligament
- Osseointegration surface: The area where the implant fuses to bone. In peri-implantitis, this area gradually disappears
Three Different States: Health, Mucositis, Peri-implantitis
The condition around an implant is evaluated in three stages. This distinction directly affects treatment decisions.Diagnostic Criteria for Peri-implantitis
According to the 2018 international consensus, peri-implantitis is diagnosed by a combination of these criteria:- Signs of inflammation: Bleeding and/or suppuration (pus discharge) on probing
- Probing depth: 6 mm or greater
- Radiographic bone loss: Loss occurring after the initial remodeling process (typically 3 mm or more from the most coronal point of the implant's intraosseous portion)
How It Differs from Periodontitis
Peri-implantitis resembles periodontitis but has some important differences:How Common Is It?
Peri-implantitis is one of the most important late complications of dental implant treatment. The literature shows that a significant proportion of individuals who receive implants develop peri-implant mucositis over time, with a portion progressing to peri-implantitis. Prevalence rates vary among studies, but they underscore the importance of close monitoring in long-term implant follow-up. Risk accumulates over years after implant treatment; rates increase significantly after 5 to 10 years of follow-up. For this reason, implant success should be evaluated not by short-term placement but by long-term follow-up.Why Is It So Important?
Peri-implantitis is a serious problem because:- Bone loss is irreversible
- If neglected, it progresses to implant loss
- Placing a new implant after implant loss is difficult
- Treatment is challenging and not always successful
- While it is easily managed in the early stage (mucositis), it requires extensive surgery in the late stage
- Prevention is far easier and more valuable than treatment
Symptoms
One of the most misleading aspects of peri-implantitis is that it usually does not cause pain in the early stages. Because an implant has no nerve, the early warning signals you would experience with a natural tooth do not occur here. For this reason, recognizing the symptoms and attending regular checkups is crucial for early detection of the disease.Early-Stage Symptoms (Mucositis Phase)
At this stage, there is inflammation only in the soft tissue; bone loss has not yet begun. Complete healing is possible with proper intervention.Advanced-Stage Symptoms (Peri-Implantitis Phase)
Once bone loss has begun, the symptoms become more noticeable. At this point, comprehensive treatment is required.- Deep periodontal pocket: Your dentist will detect a pocket of 6 mm or deeper around the implant when probing. This is one of the key findings of peri-implantitis
- Suppuration (pus discharge): When the mucosa around the implant is pressed, a yellow-white discharge appears. This is a strong indicator of active inflammation
- Mucosal recession: The mucosa around the implant begins to recede, making the metal body of the implant or the abutment visible
- Chronic bad breath: Bacterial buildup around the implant leads to halitosis
- Bad taste in mouth: A metallic or foul taste, especially upon waking in the morning
- Color change around the implant: The mucosa may take on a dark red or purple appearance
Very Advanced-Stage Symptoms
If neglected, serious symptoms emerge:- Implant mobility: This is the most critical finding. With a natural tooth, mobility indicates support loss. With an implant, mobility usually means that osseointegration has been lost and the implant is likely beyond saving
- Significant mucosal recession: The implant screw may become completely exposed
- Pain when biting: Discomfort in the implant area during normal chewing movements
- Visible swelling: Noticeable swelling and edema in the surrounding tissues
- Changes in facial contour: Slight change in facial appearance, sometimes swelling visible on the skin
- Acute abscess: An acute inflammation characterized by sudden pain, severe swelling, and pus discharge. This requires emergency treatment
The Silent Progression Trap
The biggest trap with peri-implantitis is its silent progression. Most patients experience the condition without feeling anything wrong:- Absence of pain: An implant does not send pain signals like a natural tooth. Bone loss can progress while you feel no discomfort
- Function continues: As long as the implant continues to perform its chewing function, you may assume there is no problem
- No initial aesthetic concern: While the crown maintains its natural appearance, the underlying bone loss remains invisible to the eye
- Signs may remain hidden: Especially in smokers, the signs of inflammation can be masked
Which Implants Are More Frequently Affected?
The risk of peri-implantitis is not the same for all implants. Certain characteristics increase the risk:- Posterior (back) implants: Harder to brush, more prone to plaque buildup
- Bridge-supporting implants: Connection areas that are difficult to clean
- Immediate-load implants: The risk may be slightly higher because the implant is put into function before the bone has fully integrated
- Implants in thin-mucosa areas: Lack of keratinized mucosa makes cleaning more difficult
- Implants with inadequate keratinized tissue: In cases where the band of attached gingiva around the implant is narrow, plaque control becomes harder
- Implants with cement residue: If excess cement used during crown placement remains under the mucosa, it creates chronic inflammation
Causes
The primary cause of peri-implantitis is plaque accumulation around the implant. However, not every implant responds to plaque buildup in the same way. Your immune response, risk factors, and local conditions determine whether the disease develops.Primary Cause: Plaque Accumulation
The starting point of peri-implantitis is always bacterial plaque that accumulates around the implant. When you don't clean your implant properly, plaque builds up at the implant-mucosa junction and triggers inflammation. This inflammation initially stays in the soft tissue (mucositis), but if left uncontrolled, it spreads to the bone and develops into peri-implantitis.Risk Factors
In addition to plaque accumulation, many risk factors influence the development of peri-implantitis. The combination of these factors determines your individual risk.Anatomical and Surgical Factors
- Implant position: Implants placed too buccally (toward the cheek) have thin surrounding bone, increasing the risk of recession and peri-implantitis
- Insufficient interdental bone: When the distance between an implant and the adjacent tooth or implant is inadequate, plaque accumulation increases and bone loss accelerates
- Angled implants: Implants placed at an angle can create areas more prone to plaque accumulation
- Implant surface characteristics: Different implant systems have surface features that can create varying risk profiles
- Sinus region implants: Anatomical limitations in the upper posterior region can increase risk
Lifestyle and Systemic Factors
- Poor oral hygiene habits: Neglecting to brush twice daily and use floss and interdental cleaning once daily
- Inadequate nutrition: Deficiencies in vitamins C and D, protein, and omega-3 affect your immune response
- Stress: Suppresses your immune system, and oral hygiene may be neglected
- Osteoporosis: Affects bone density and can create a foundation for peri-implant bone loss
- Bisphosphonate use: Bisphosphonates alter bone remodeling. Careful evaluation is needed during implant planning
- Immune suppression: Chemotherapy, immunosuppressant use after organ transplantation
- History of radiotherapy: Head and neck radiotherapy affects bone healing and inflammatory response
Prosthetic and Restorative Factors
- Crown margin too close to mucosa: Creates an area prone to plaque accumulation
- Improper emergence profile: If the crown's emergence profile from the gum is not smooth, plaque control becomes difficult
- Loss of contact with adjacent tooth: Can lead to food impaction, increasing inflammation risk
- Loose connection: Loosening at the implant-abutment connection creates micromovement and can trigger inflammation
Bruxism and Parafunctional Habits
- Nighttime teeth clenching or grinding: Applies excessive force to your implant. A night guard can be protective
- Daytime teeth clenching: Particularly pronounced during stressful periods
- One-sided chewing: Places disproportionate load on certain implants
- Biting hard objects: Habits like biting ice, seeds, or pens
Combined Effect of Risk Factors
Why Are Some Implants at Risk While Others Are Not?
A common question in clinical practice: "Why did some implants in the same mouth stay healthy while others developed peri-implantitis?" There are several explanations:- Cleaning accessibility: Some implants are easier to clean due to anatomical reasons
- Local anatomical differences: Bone thickness and the amount of keratinized mucosa vary among implant sites
- Prosthetic design: Some crown profiles are easier to clean
- Loading differences: Certain implants receive more chewing force
- Adjacent conditions: If there is inflammation at an adjacent tooth, that implant may also be affected
Stages
Peri-implantitis does not develop suddenly. It is a gradual process that ranges from plaque accumulation to implant loss. For practical clinical use, it is helpful to classify the disease into four stages. Each stage has distinct clinical findings, radiographic features, and treatment approaches.Bone Loss Patterns
The shape of bone loss in peri-implantitis influences treatment decisions:- Horizontal bone loss: The bone surface descends uniformly. Responds less favorably to regenerative therapy
- Crater-shaped (saucer-shaped) bone loss: Crater-like, four-walled defect around the implant. Specific to peri-implantitis. May respond better to regenerative therapy
- Buccal dehiscence: Bone loss on the front surface of the implant. Often accompanied by gum recession
- Combined defects: Cases where horizontal and vertical loss occur together
Should Not Be Confused with Initial Bone Remodeling
Progression Rate
The rate of peri-implantitis progression varies:- Slow-progressing cases: Mild loss over years. Seen in individuals with low risk factors
- Moderate-progressing cases: Significant bone loss over months to years
- Rapid-progressing cases: Severe loss within months. Often a combination of periodontitis history, smoking, and neglected care
Follow-Up and Monitoring
Whether peri-implantitis is progressing is monitored using these parameters:- Standardized X-rays: Bite-wing or periapical X-rays taken at the same angle and settings. For comparison over the years
- Probing depth: Measured at 6 points per implant at each checkup
- BOP (bleeding on probing): An indicator of active inflammation
- Clinical photographs: Tracking visual changes
- Baseline values: Reference values taken immediately after implant treatment is completed
Diagnostic Methods
Diagnosing peri-implantitis requires a different approach than periodontitis around natural teeth. The most critical difference is the need to know baseline reference values (taken immediately after implant treatment is completed). Without these references, distinguishing normal remodeling from pathological bone loss can be difficult. The diagnostic process begins with the patient's history, continues with clinical examination, and is completed with periodontal probing and X-rays.Detailed Patient History
- Implant treatment history: When was it placed? Which crown was used for restoration?
- Treatment history: Was bone grafting performed, sinus lifting, other surgeries?
- Onset of symptoms: How long have bleeding, swelling, or discomfort been present?
- Previous follow-up intervals: Whether regular follow-up appointments were attended, timing of the last check-up
- Periodontal disease history: Has periodontitis occurred before?
- Smoking: Amount and duration
- Diabetes status: HbA1c level, control status
- Systemic diseases and medication use: Bisphosphonates, immunosuppressants
- Oral hygiene habits: Brushing technique, interdental cleaning, use of special floss
- Bruxism: Night clenching, grinding, use of night guard
Clinical Examination
The dentist systematically evaluates the following parameters:- Mucosal color, consistency, and texture: Redness, swelling, shininess
- Plaque accumulation: Around the implant and on the crown surface
- Mucosal recession: Presence and degree
- Keratinized mucosa width: Band of attached mucosa around the implant
- Crown and restoration evaluation: Margin fit, cement remnants, contact points
- Implant mobility: Normally should not exist; presence indicates loss of osseointegration
- Occlusal evaluation: Are there areas experiencing excessive load?
- Periodontal status of adjacent teeth: If underlying periodontal disease is present
Peri-implant Probing
A technique similar to periodontal probing around natural teeth is used, but with some important differences:- Light pressure: Probing should be performed with light pressure of 0.25 N. Excessive pressure can damage the mucosa
- Six points per implant: Measurements at different points on mesial, distal, buccal, lingual surfaces
- Pocket depth recording: Depth of each point in millimeters
- Bleeding assessment: Does bleeding occur after probing?
- Suppuration check: Does pus discharge with gentle pressure?
X-ray Evaluation
X-rays are an indispensable tool in diagnosing peri-implantitis. Bone loss can only be definitively detected with X-rays.Measuring Bone Loss
Bone loss on X-rays is measured according to these reference points:- The most coronal point of the implant's intraosseous portion: Typically the thread beginning or implant surface transition point
- The highest point of bone: The current level of bone around the implant
- Distance between: The amount of loss is measured in millimeters
Additional Assessments
Depending on the case, the following assessments may also be performed:- Implant mobility assessment: Implant stability is measured with special devices (Periotest, Osstell)
- Microbiological tests: Bacterial profile evaluation in treatment-resistant cases
- Systemic blood tests: Diabetes screening, immune system evaluation
- Occlusal analysis: Detailed bite analysis for implants experiencing excessive load
Differential Diagnosis
Other conditions present findings similar to peri-implantitis:What Happens If Left Untreated?
When peri-implantitis goes untreated, it does not stop progressing. The disease silently leads to bone loss and can ultimately result in implant failure. In this section, we examine the short-term and long-term consequences of untreated peri-implantitis.Ongoing Progression of Bone Loss
The most significant feature of peri-implantitis is that its progression is non-linear and accelerates over time. Bone loss that takes years around natural teeth can reach similar levels around implants within months.Implant Loss
The most serious consequence of untreated peri-implantitis is implant failure. This process unfolds as follows:- Initial bone loss: Bone surrounding the upper portions of the implant begins to erode
- Reduction of osseointegration area: The implant-to-bone connection weakens
- Onset of implant mobility: Over time, slight movement of the implant becomes noticeable
- Noticeable looseness: Once a large portion of osseointegration is lost, the implant begins to wobble
- Implant failure: Eventually, the implant either falls out on its own or must be removed
Impact on Adjacent Teeth and Implants
Peri-implantitis may not remain a localized problem:- Impact on adjacent teeth: As bone loss progresses, the periodontal health of neighboring teeth can also be affected
- Spread to adjacent implants: If there are multiple implants in the mouth, there is a risk that peri-implantitis will spread
- Bacterial reservoir: An infected implant becomes a constant source of bacteria for other areas of the mouth
- Systemic bacterial load: Chronic oral infections contribute to the systemic inflammatory burden
Acute Flare-Ups
Chronic peri-implantitis can sometimes become acute:- Sudden swelling: Noticeable swelling around the implant
- Severe pain: Even though the implant itself has no nerve, acute inflammation in surrounding tissues causes pain
- Pus discharge: Accumulation of large amounts of pus
- Fever and general fatigue: In severe cases
- Facial swelling: If inflammation spreads to surrounding tissues
Aesthetic Consequences
Functional Consequences
- Chewing impairment: When the implant begins to loosen, chewing efficiency decreases
- Pain and discomfort: Discomfort during chewing
- Food impaction: Following mucosal recession and bone loss
- Change in bite: Disruption of bite balance if the implant is lost
- Impact on speech: Especially with mucosal recession in front-region implants
Challenges After Implant Loss
When an implant is lost due to peri-implantitis, replacing it presents many challenges:- Reduced bone volume: The lost bone may be insufficient for a new implant. Bone grafting becomes necessary
- Soft tissue loss: Mucosal recession may require grafting for an aesthetic outcome
- Bacterial risk persists: If the risk factors that contributed in the same mouth continue, similar problems may develop with the new implant
- Increased cost: Treatment significantly expands with bone grafting, soft tissue grafting, and healing time
- Extended timeline: Re-treatment can take months
- Longevity concerns: A history of peri-implantitis also increases the risk for the new implant
Narrowing of Treatment Options
When peri-implantitis is treated early, non-surgical methods are often sufficient. In later stages, options narrow:- Mucositis (Stage 1): Professional cleaning and improved home care alone may be sufficient
- Early peri-implantitis (Stage 2): Non-surgical cleaning, minor interventions
- Moderate to advanced peri-implantitis (Stage 3): Surgical treatment, consideration of regenerative techniques
- Very advanced peri-implantitis (Stage 4): The implant is usually not salvageable, removal and rehabilitation required
Indirect Effects on Systemic Health
As a chronic infection, peri-implantitis can have systemic effects:- Cardiovascular risk: Chronic oral infections contribute to the systemic inflammatory burden
- Diabetes control: Chronic infection can make blood sugar control more difficult
- Immune burden: Constantly fighting an active infection places a burden on the immune system
How to Prevent It
Peri-implantitis is largely preventable. The success of implant treatment is not measured only by surgical placement, it is determined by implementing a long-term prevention strategy. In this section, we address both primary prevention (preventing disease before it starts) and secondary prevention (preventing progression of existing mucositis or peri-implantitis).Daily Implant Care
Plaque control around the implant must be more careful than around natural teeth. Standard brushing is often insufficient.Professional Maintenance Care
Professional maintenance care after implant treatment is the fundamental determinant of the implant's long life. If this care is neglected, the risk increases significantly.- 3 to 6 month maintenance visits: This is the standard recommendation. The interval is determined according to individual risk
- 3 month intervals for high-risk groups: History of periodontitis, smokers, diabetics, individuals with multiple implants
- Professional plaque cleaning: Special instruments that do not damage the implant surface are used (plastic curettes, ultrasonic devices with special tips)
- Peri-implant probing: Pocket depth is measured and bleeding is recorded at each visit
- X-ray monitoring: Annually or every two years (depending on individual risk)
- Oral hygiene education: Your oral hygiene techniques are reviewed at each visit
- Early detection of signs: Redness, bleeding, mucosal changes are caught early
Management of Risk Factors
- Quitting smoking: One of the most important modifiable factors for implant success. Healing improves significantly after quitting
- Diabetes control: Meeting HbA1c targets is a fundamental determinant of peri-implant health
- Maintaining periodontal health: Gingivitis or periodontitis in natural teeth should be treated
- Bruxism management: Night guard reduces excessive force on the implant
- Stress management: For immune response and bruxism
- Balanced nutrition: Vitamins C and D, protein, and omega-3 balance the inflammatory response
- Adequate sleep: For regular function of the immune system
Prevention During Surgical Planning
Peri-implantitis risk actually begins to be controlled during the planning phase before implant placement:- Comprehensive pretreatment evaluation: Treatment of existing periodontal conditions, smoking cessation, diabetes control should be completed before implant placement
- Adequate bone assessment: Three-dimensional planning with CBCT
- Appropriate implant positioning: Safe position within the bone, adequate distance from adjacent structures
- Keratinized mucosa evaluation: If insufficient, it can be increased with grafting
- Appropriate prosthetic design: Structure that allows plaque control and is cleanable
- Preference for screw-retained restorations: Eliminates the risk of residual cement
Recommendations for Risk Groups
Importance of Maintenance Visits
For individuals with dental implants, maintenance visits should be considered as "implant health checks" rather than just "dental exams":- Early detection: Caught at the mucositis stage
- Detection of plaque accumulation areas: Improvement of home care
- Occlusion evaluation: Is there an implant under excessive load?
- Prosthetic evaluation: Are there problems at the crown margin, residual cement?
- Comparison with baseline: Probing and X-ray values are compared with initial measurements
- Individual risk update: Changing conditions (new medication, new illness) are monitored
Frequently Asked Questions
Can peri-implantitis be treated?
Can I get a new implant if I lose mine?
My implant is bleeding—what should I do?
Will my implant be saved if I quit smoking?
How can I tell if I have peri-implantitis? What are the symptoms?
Can I use dental floss for my implant?
How often should I come in for check-ups to prevent peri-implantitis?
I lost all my teeth and had all-on-four—is my peri-implantitis risk high?
Content Information
This page was prepared by the Dore Medical Editorial Board and medically reviewed by Dr. Merve Özkan Akagündüz.